6x12 is called “Adjustment Protocol” and as I’ve started to rewatch 6x09, I might have found a hint to what that may mean.
When Gabriel talks about the red sun toxin and how will he monitor Octavia the whole time she will be under the influence of the toxin, he said that he will be acting as her guide, who they call an adjuster.
So adjusting protocol might mean bringing into serum someone who will keep the influenced alive/sane/unharmed/we don’t know really yet.
We know that Madi in a chair takes place next week, in Bob’s episode 6x11, so what might be happening in 6x12? Who will be an adjuster, or even what?
Gabriel was said to think he can walk on water because of the serum. Also known as the red sun toxin Murphy was poisoned in 6x02. With its pure form it opens wrong parts of the mind. But somehow Sanctum found it a way to check if there’s still a host, it brought Murphy to hell with its pure form, and made people discover or even heal parts of the mind by Gabriel’s modification. Maybe that’s the part when Gabriel won over sanctum and did better.
And also it’s all connected to discovering anomaly’s needs and messages. And those messages can be discovered once influenced person is able to do it, and when there is an adjuster, who can control everything on the outside and affect the inside of one’s head. (Just like Bellamy somehow did with Clarke in 6x10)
Adjustment protocol might be connected to the red sun toxin, someone going through hell or exploring the mindspace full of anomaly and someone else taking a main role in keeping them alive.